tobacco use risks Cigarette Smoking | Smoking and Health Problems Caused by Secondhand

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The respiratory mucosa exists both in the nose and in the trachea and bronchi ( Cigarette smoke has been reported to induce inflammatory cell infiltration, especially of neutrophils, as well as cell division and mucus hypersecretion ( + lymphocytes, neutrophils, and eosinophils, suggesting that CSS exposure in the allergic condition could induce appreciable histological changes, although the dose and number of CSS administrations were insufficient to influence non-allergic mice

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Cigarette smoke contains high levels of reactive oxygen species (ROS) 11,12 and produces additional ROS upon exposure to human bronchial epithelial (HBE) cells 10,13