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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention

Less supported scenario: If your B12 status is already normal, extra B12 has not been shown to consistently boost energy in otherwise healthy people

No specific interactions have been documented that make these combinations dangerous

Injections We like to keep 3ml and 12ml syringes on hand

The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety