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shifts to internal hotspots To confirm that N-terminal aza-substitution protects the canonical DPP-4 site in a physiological context, we performed tandem mass spectrometry (MS/MS) fragmentation analysis of three analogues (Aib8, AzaA8, and AzaH7) in mice

In our study, a marked accumulation of the colocalization of bound/free GTP with small GTPases Arl8b and Rab7 in both genotypes suggests a lack of endolysosomal mobilization in old age neurons

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