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Together, these findings indicate that achieved weight loss alone did not recapitulate the favorable cardiovascular pattern observed across attained semaglutide dose tiers, particularly in a setting where semaglutide prescribing after maximum weight loss was minimal

Ozempic is approved for the treatment of type 2 diabetes, while Semaglutide is approved for the treatment of obesity as defined by body mass index above 30

Patient reports are mixed

Weeks 13 to 24 (10 to 15 mg): Full therapeutic benefit

Acknowledgments The authors thank the external reviewers, Allan Grill MD, CCFP (COE), MPH, FCFP, CCPE and Kelly Picard PhD, RD, CDE, for their insightful feedback and for the lending of their time and expertise