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While the study did not include follow-up ICP measurements, the reduction in the Frisen grade and retinal nerve fiber layer (RNFL) thickness served as surrogate markers for ICP reduction

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76 Diabetes-associated CVDs, including coronary artery disease and diabetic cardiomyopathy, are commonly classified as macrovascular and microvascular complications, respectively, on the basis of the underlying pathological changes observed in DPD