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Interestingly, the crystal structure of the SOCS2Elongin B/C complex revealed that the C-terminus of the SOCS box and the N-terminus of the extended SH2 subdomain (ESS) can interact and maintain the stability of the SH2SOCS box domain interaction (131)

doi: 10.4049/JIMMUNOL.155.3.1151 25 AlhazmiANekouaMPMichauxHSaneFHalouaniAEngelmannIet al

When tested for their ability to prevent the protein denaturation effect, parsley extract again showed superior activity (278)

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