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Rothe et al

Some individuals find extending the time at each dose level beyond the standard four weeks helpful

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Certainly, hyperglycaemia (or oral glucose tolerance) did not turn out to be a strong predictor of GLP-1 secretion, suggesting that other characteristics of type 2 diabetic patients not represented by elevated glucose concentrations in the fasting or postprandial state may determine GLP-1 secretion, although opinions differ [54]