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Total RNA isolation, cDNA synthesis, and qRT-PCR TransZol RNA kit (ET101-01, TransGen Biotech) was used to extract total RNA from Arabidopsis plants according to manufacturers instructions

In children, therapy may continue for several years until an acceptable height is achieved or until growth plates close

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It is formulated with 0.9% Benzyl Alcohol added as a bacteriostatic preservative

This strategy is needed not only to provide foundational evidence for the safety and efficacy of senescent cell removal, but also to begin collecting much needed biomarker data that could be used as surrogate markers for senescent cell identification and tracking in pre-clinical/prodromal disease stages