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It might be more affordable to take a more potent drug, Fitch says.

Medications Semaglutide, Tirzepatide Monthly Cost $39-$299 Speed to Start Fast Trustpilot 3.2 / 5 (5940+ reviews) Est

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Tirzepatide, which acts on both GIP and GLP-1 receptors, appears to have a somewhat more favorable GI tolerability profile, possibly because GIP receptor activation partially counteracts the nausea-inducing effects of GLP-1 agonism