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Photodynamic therapy with decacationic [60]fullerene monoadducts: effect of a light absorbing electron-donor antenna and micellar formulation

X.TanC.GuillenJ.PauliM

10.1016/j.nbd.2019.01.025 188

doi: 10.3389/fphar.2021.772510

According to a study of PT-141 for use in erectile dysfunction, it causes the following side effects at a dose of 10 mg when taken intranasally: Nausea (12.8%) Flushing (10.5%) Diaphoresis / excessive sweating (9.3%) Low back pain (7.0%) Taste disturbance (4.7%) Headache (3.5%) Somnolence / drowsiness (1.2%) It is important to note that these side effects are observed at a dose of 10 mg, which is higher than the dose used in the LOVER Protocol, which uses 2000 mcg