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Similarly, the expression of key autophagy genes, such as ATG5 , ATG7 , and BECN1 , is downregulated during normal aging in the human brain [209]

Human molecular genetics 18 , 23882399, doi:10.1093/hmg/ddp178 (2009)

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BAC water is naturally near pH 5.5, which is a chemically reasonable solvent for the entire blend without further buffering

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