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This is because some people with more weight experience hormonal imbalances and abnormal ovulation, making it more difficult to get pregnant, says Dr

However, when combined with insulin or sulfonylureas (in patients with diabetes), the risk of low blood sugar increases significantly, which can manifest as fatigue, weakness, and other symptoms

Wang YX, Xiang C, Liu B, Zhu Y, Luan Y, Liu ST, Qin KR (2016) A multi-component parallel-plate flow chamber system for studying the effect of exercise-induced wall shear stress on endothelial cells

If that describes you, this is worth flagging explicitly to your doctor before any treatment decision

Many people who reduce their weight on GLP-1s experience improved mood, including fewer depressive symptoms [130,132,133]