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General: Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where B12 is deficient
Months 1-3 Initial response phase Many patients reach their goal here and stay long-term no escalation needed
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2 The electrophoretic mobility of G6PD Mediterranean is identical to that of G6PD B, but its catalytic activity is markedly reduced, and hemolysis can be severe (Class II)
But a delayed train, a missed connection, an unexpected extra night somewhere rather wonderful these things happen, and having a small buffer keeps your treatment on track whatever the journey throws at you
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