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Some semaglutide may absorb through the esophageal or gastric mucosa, though this contribution is likely minimal compared to sublingual absorption
During the transition: Monitor blood glucose more frequently for the first 4 to 6 weeks Expect potential hypoglycemia risk if also taking insulin or sulfonylureas Your provider may need to adjust other diabetes medications A1C improvements may be more pronounced with tirzepatide The SURPASS clinical trials demonstrated that tirzepatide 15 mg reduced A1C by up to 2.58%, compared to semaglutide 1 mg which reduced A1C by 1.86%
10mg vial + 2mL BAC water 5mg/mL (5,000mcg/mL)
Look for cloudiness, particles, color changes, or sediment
For women of childbearing potential experiencing severe nausea, pregnancy testing may be warranted, as semaglutide is not recommended during pregnancy
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