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This guidance has the potential to change millions of lives for the better. In the U.S., the Food and Drug Administration advises people to use nicotine replacement therapies when they want to quit

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A factorial KruskalWallis rank sum test ( = 0.05) was used to identify groups with significantly different abundances between categories (all-pairs-all comparisons), and then the log LDA score (threshold = 4.0) was used to estimate the effect of each discriminant feature