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The discreetly high incidence of chronic fatigue observed in our cEDS cohort is in line with previous observations that emphasized that in EDS this issue is more common than in the general population and likely contributes to the patients functional impairment, psychological distress, and decreased QoL [86,87,88,89]

The funding sources had no role in the study design, data collection, data analysis, data interpretation, writing of the manuscript, or in the decision to submit the manuscript for publication

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the team was still part-time, but Ed Carpenter drove for nines races starting at the 2011 Indianapolis 500

These small precautions can help reduce the likelihood of strong odors developing due to spills or pet accidents