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Per capita consumption of Cigarettes in India amongst lowest in the World Over the last three decades, the legal cigarettes share of total tobacco consumption in India has declined from 21% in 1981-82 to 10% in 2023-24

And, if present, the testing protocol would therefore be performed in a substandard manner, and under substandard conditions, and any results obtained should be considered inherently unreliable

This pharmacologic evidence insinuates that nicotine modulates its responses through a nicotinic acetylcholine receptor (nAChR) and that calcium acts as a downstream effector