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Stage Four: Pre-Cancerous Lesions DNA mutations result in the appearance of visible lesions in the mouth's lining: Leukoplakia: White spots that cannot be removed Erythroplakia: Red patches (high risk for developing cancer) Oral Submucous Fibrosis (OSMF): Increasing stiffness of the mouth with difficulty opening Step 5: Cancerous Change After years of repeated exposure, genetic changes result in cancer that will then grow and spread into adjacent tissues until ultimately reaching the lymph nodes in the neck and even other organs

The accessibility of such structures will spur advancements on two levels: (i) understanding the role of sugar moieties in a variety of biological processes

Diverse mutational events probably contribute to the high CR phenotype, analogous to the myriad transcriptional changes that converge on individual dysregulated pathways across multiple cancer types (15)

We would love to hear about your experience using fSTARS and your findings!