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They are in a critical stage of development, and nicotine and THC can negatively interfere with this process

[see Adverse Reactions (6)] Nikki contains 3 mg of the progestin DRSP which has anti-mineralocorticoid activity, including the potential for hyperkalemia in high-risk patients, comparable to a 25 mg dose of spironolactone

Some doctors and patients have seen diminished cravings for nicotine, alcohol and even opioids as a unexpected side effect

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