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A stock solution of methylglyoxal (Sigma-Aldrich, M0252) was prepared at 0.1 mg/mL (1.37 mM) in culture medium, and a 3-fold serial dilution was likewise performed across six concentrations

It will also help them to have a better synergy as they age

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Research indicates that NRT is generally most effective when the patch is combined with a more rapidly absorbed form, such as gum or a lozenge