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In Japan, HTPs accounted for over 30% of the nicotine market by volume in 2023, with Philip Morris Internationals IQOS holding a dominant share, as stated by the National Institute of Public Health of Japan

247,248,249 However, these associations were not observed in non-European populations, underscoring potential ethnic differences in genetic susceptibility to hyperuricemia-related metabolic abnormalities

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Higher-income consumers may exhibit more inelastic demand for luxury goods, while lower-income consumers are more sensitive to price changes in essential goods

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