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These tobacco smoking-respiratory findings were supported by multivariable MR analyses accounting for alcohol and cannabis use and abuse, which in addition to the broadly consistent IVW results (within the IVW MR 95% confidence interval but typically less precise) with estimates from the weighted median, weighted mode, and MR Egger sensitivity analyses strengthen causal inference

Harry Wake, from IQOS a tobacco heating system that, unlike cigarettes, produce no fire, ash, or smoke said: The cost of cigarettes is clearly a huge factor for many smokers seeking cheaper and less harmful alternatives

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