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9 Cardiovascular Risks: Nicotine in dipping tobacco can lead to increased heart rate and blood pressure, potentially contributing to cardiovascular problems

Canker sores or other ulcers may vary in size, severity, and healing time depending on the specific subtype

Paul gives us the answer

In its most recent publication on smoking, the World Health Organization pointed out that, among the eight main causes of death in the world today, six are associated with tobacco exposure, among them we stress inflammatory and infectious diseases of the respiratory tract.1 According to data from the Ministry of Health (2006), 16.2% of the adult Brazilian population smoke cigarettes daily.2 Despite the broad advertisement in the media about the harmful effects of cigarette smoking, very little is known about the association between cigarette exposure and the development of associated disorders such as chronic rhinosinusitis (CR)

Strictly optional, but I have it from a friends Irish priest that this a pretty good idea