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In March 2018 the Campaign for Tobacco-Free Kids, American Cancer Society, American Heart Association and other groups (including pediatricians) filed an e-cigarette lawsuit against the FDA for its proposed delayed 2022 deadline that does nothing to address concerns about the health threat e-cigarettes pose because they continue to be sold virtually unregulated

Research using high oxygen tension (hyperoxia) in neonatal mice demonstrated that oxidative stress induces reactive oxygen species, cell death, and disruptions in hippocampal circuits (Mandic-Maravic et al., 2019)

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