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This disparity is also evident in South Asia, where a study in India reported that tobacco use was considerably higher among Indigenous groups for both smoking (25%) and smokeless forms (36%), compared to that among non-indigenous counterparts (18% and 19%, respectively) [6]

This review discussed the significant effect that E-cig use had on the BC tumor microenvironment, which ultimately led to enhanced tumor malignancy and metastasis, with an emphasis on the extent that E-cig uses had on the crosstalk between cancer and immune cells, as well as the potential underlying mechanisms that drive this aggressive phenotype of BC