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People with laryngectomies are severely disfigured, and a lot of this happened because of a lifetime of addiction. According to several studies, nicotine is more addictive than heroin

American Indians use the dried leaves for prayers, tobacco ties, ceremonies, offerings, blessings, and gifts

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The piece from MHSP links to a number of research papers including one from a group of eminent US psychiatrists that concluded after their study: Ecigarettes appeal to those with mental illness as a viable alternative to combustible tobacco, and their use does not appear to exacerbate nicotine addiction or psychiatric symptoms

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