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For heavy smokers, it might take a week (and possibly longer) for the cotinine traces to leave your urine or remain so small that they are undetectable

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This individual brushes his teeth twice a day but does not floss or use dental mouthwash or interdental brushes

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[19] Accordingly, similar to the marketing efforts of e-cigarette companies, it is clear through promotional efforts by the tobacco companies selling oral nicotine products that they are incentivizing continued and uninterrupted use of their product in perpetuity and gaining significant appeal from youth who may not currently smoke, thereby potentially initiating or prolonging nicotine and tobacco dependence