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Statistical analysis used generalized estimating equations logistic regression models to account for repeated observations from the same individuals across multiple survey waves while controlling for demographic factors including age, gender, ethnicity, income, education, and country

Alberta does not set a provincial nicotine cap, meaning strengths above 20 mg/mL (such as 50 mg/mL) are not specifically prohibited

The bag is sold as-is, and the tobacco is not consumable

Dopamine has been termed the pleasure neurotransmitter because it causes pleasurable feelings when it binds to its receptors (dopamine receptors) in the reward pathway