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Furthermore, using an in vitro approach to examine receptor-G protein coupling, we have shown unique effects of adolescent fluoxetine and nicotine exposure on 5-HT 1A R function

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A large body of research also shows that reduced nicotine content cigarettes do not lead smokers to compensate for lower nicotine by smoking more

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"FDA hopes the recommended changes will allow more people to use these products effectively for smoking cessation and that tobacco dependence will decline in this country." The changes that the FDA is recommended include a removal of the warning that consumers should not use an NRT product if they are still smoking, chewing tobacco, using snuff or any other product that contains nicotine--including another NRT