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This finding may reflect progressive maturation of brain development during adolescence, increased tolerance to low-to-moderate tobacco SHS exposure, greater time spent outside the home, or potential confounding effects of active smoking behaviors emerging during adolescence 33,34

3 In 2020, 4.6% of adults in Indiana used smokeless tobacco.3 In 2018, 18.5% of high school students in Indiana used e-cigarettes on at least one day in the past 30 days.2 In 2018, 3.8% of high school students in Indiana used chewing tobacco, snuff or dip on at least one day in the past 30 days.2 In 2018, 6.7% of high school students in Indiana smoked cigars, cigarillos or little cigars on at least one day in the past 30 days.2 Economics of tobacco use and tobacco control Indiana cigarette tax Indiana received $548.6 million (estimated) in revenue from tobacco settlement payments and taxes in fiscal year 2021.4 Of this, the state allocated $7.5 million in state funds to tobacco prevention in fiscal year 2020, 10.2% of the Centers for Disease Control and Preventions annual spending target.4 Smoking-related health care costs: $2.93 billion per year4 Smoking-related losses in productivity: $3.17 billion per year5 Indiana tobacco laws Indiana smoking laws Tobacco taxes Indiana is ranked 39th in the U.S

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World J Gastroenterol 18:21802187 WHO (2023): Tobacco

These two flavors also had the most complex flavor descriptions: About 20 percent of tadpoles exposed to a flavor of strawberry, almond, caramel, vanilla, biscuit, Vienna cream and 70 percent of those exposed to a flavor of cereal, berries, cream, citrus developed clefts