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Additionally: The wetter the chewing tobacco, the more nicotine is absorbed during chewing

In the 1990s Germany was a focus for advertising, and between 1993 and 1997 the smoking rates among women aged 1225 in Germany went from 27% to 47% even though the increase in mens smoking for the same age group is much smaller

Another limitation is due to the self-report nature of the survey, which makes it susceptible to social desirability bias

FDA authorized PMI to market IQOS with the claim that switching completely from conventional cigarettes to IQOS reduces consumer exposure to harmful chemicals, even though most members of an official FDA advisory panel of experts were skeptical of the claim