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Human lung tumor tissue specimens The treatment naive tissue specimens from 121 patients with EGFR WT NSCLC who have received EGFR TKI treatments (Supplementary Table 1) were obtained following the guidelines approved by Institute of Research Board Committee at China Medical University Hospital (DMR101-IRB1-120), and written informed consent was obtained from patients in all cases

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Rex also tried them and he would say that they took one at the beginning, but little by little they changed the routine

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