There is a strong correlation between those who smoke and those that develop cancer, or a wide range of respiratory, heart, or immune diseases
Add the health warning space regulators mandate (30% to 50% or more of the front and back panels, depending on the country,) and you get a spec sheet that bears little resemblance to the simple number most people think is the whole story
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doi:10.1136/tobaccocontrol-2016-053030
However, nicotine alone is relatively harmless, and switching from daily tobacco smoking to daily e-cigarette use can be an important step for people to stop smoking completely