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Experiences in many countries, states, and other jurisdictions demonstrate that a comprehensive approach to address illicit tobacco markets is most effective

Pre-clinical and clinical studies related to BC have shown that E-cigarettes can trigger cancer-related damage to bladder tissues in mice 28 , and the urine of 92% of E-cigarette users tested positive for two chemicals, o-toluidine and 2-napthylamine, known to cause BC 29

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Fast-acting formats like vaping allow for more controlled intake compared to smoking, but nicotine remains an addictive stimulant