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Cannabis and health Cannabis primarily acts on the body's endocannabinoid system and can have both medical and psychoactive effects: Short-term effects: relaxation, altered perception, increased appetite Risks: concentration disorders, anxiety, possible addiction Long-term risks: possible effects on mental health with frequent use Compared to alcohol, cannabis is often rated in studies as less physically toxic, but not risk-free

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"The rise of Glasgow in the Chesapeake tobacco trade, 17071775." William and Mary Quarterly pp: 179199