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Endothelial cells submerged with blood serum from both the people who had regularly smoked and those who regularly vaped released less nitric oxide which means that the endothelial cells were functionally impaired

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A comprehensive review published by the American Thoracic Society concluded: Regular smoking of marijuana by itself causes visible and microscopic injury to the large airways that is consistently associated with an increased likelihood of symptoms of chronic bronchitis that subside after cessation of use

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Since June 2019, more than 1,000 cases of vaping-associated lung injury have been reported.2 The reason for the sudden onset of this new epidemic remains poorly understood, though increasing evidence suggests that the syndrome may be related to use of vaporizer cartridges modified with THC or other additives