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Interaction 2 Nicotine Speeds Caffeine Clearance Smokers metabolise caffeine twice as fast as non-smokers Nicotine induces liver enzymes (CYP1A2) that significantly accelerate caffeine metabolism smokers clear caffeine from their system approximately twice as fast as non-smokers

Smuggled international cigarettes, growing rapidly in the country, do no use Indian tobaccos, posing a direct threat to the domestic tobacco demand with huge livelihood implication for 45.7 million people employed in the sector, said the statement

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With the exception of the coefficient describing net smuggling to Canada, all estimates are of the expected sign, and nearly all are statistically significant at the 1% level