The self-medication hypothesis suggests that schizophrenia patients smoke, in part, to alleviate negative symptoms, dysphoric mood, and neurocognitive impairments by ameliorating a dysfunctional dopamine system.10 The addiction vulnerability hypothesis suggests that genetic and neurobiological factors associated with schizophrenia (ie, alterations in nicotinic acetylcholine receptors [nAChRs] and central dopamine systems) may predispose schizophrenia patients to nicotine addiction.11 Examining the effects of tobacco smoking on neurocognition in schizophrenia is crucial because it may help clarify the rationale for high consumption of tobacco products and inform treatment interventions
[60] That same year, she performed a medley of Stephen Sondheim songs during the In Memoriam segment at the 64th Annual Grammy Awards, alongside Rachel Zegler, Leslie Odom Jr
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I certainly have my own experiences. As for what the experience was like filming the show, it was a brief and solitary one, says Curtis
