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Here, using a multi-armed ICSS bandit task, we show that mice passively treated with nicotine forage more frequently at locations with the highest probabilities of reward (P 50 and P 100 ) compared to non-exposed animals, suggesting a bias in the exploration/exploitation trade-off toward decreased exploration

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Nicotine can also relax the sphincter of Oddi in experimental models and might reduce sphincter spasm and obstruction which can cause PEP (12)

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