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Estimated glomerular filtration rate (eGFR) was calculated using the modification of diet in renal disease study (MDRD) formula and defined as CKD below eGFR 60 ml/min/1.73 m 2

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They are not a perfect model. While Kheradmand also acknowledges that the findings cannot be directly applied to people, she says: I cannot imagine the process in humans would be very different. Ravi Kalhan, director of the Asthma and COPD Program at the Northwestern University Feinberg School of Medicine agrees that there is uncertainty in terms of how the findings apply to humans