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As highlighted previously nicotine may interfere with OCT proteins in transporting drugs to organs and tissues (Bergen et al., 2014)

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Additionally, tobacco use can augment the risk of tuberculosis (TB) infections, which primarily affect the lungs but can potentially spread to other parts of the body, endangering overall health

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Check these signs: Brown or yellow spots Old cigarettes are often dotted with dark brown or yellow spots, which comes from moisture and oils leaching out of the tobacco Dull smell Stale cigarettes will smell papery, plain, or otherwise will not leave a very strong impression Tobacco falling out Due to decreased moisture, the tobacco inside a stale cigarette will dry out