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Tobacco constituents generate reactive oxygen species (free radicals) that damage cellular structures, including hepatocyte membranes and mitochondria

Clinical Psychology Review, 32 (2), 105121

Pros: No nicotine, no tobacco, provides a mild energy boost, familiar pouch format Cons: Caffeine sensitivity may be an issue for some, doesn't replicate the nicotine "hit" Best for: People quitting nicotine who still want a stimulant effect, or anyone seeking an afternoon pick-me-up without coffee 4

Sources: Smoke Inhalation. WebMD

Neurodegenerative diseases may ultimately be caused by your habits, routines, and choices in life