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Step 3: Make a Loose Twist or Fold If you want to prevent the joint from burning or unraveling, loosely twist the paper at the tip or fold the paper gently to close it off

Smoking greatly increases the risk of cardiovascular diseases, including heart attacks, strokes, and peripheral artery disease

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Among men, the pooled relative risk for coronary heart disease was 1.48 for smoking one cigarette per day and 2.04 for 20 cigarettes per day, using all studies, but 1.74 and 2.27 among studies in which the relative risk had been adjusted for multiple confounders