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The disease corky ringspot of potatoes was first reported in the United States in 1946, and was identified incorrectly as a novel virus until advances in genetics demonstrated it to be the result of TRV

Long-term stress is proposed to have direct effects on asthma through long-term hypothalamic-pituitary-adrenocortical activation, which leads to a decrease in B2 adrenergic and glucocorticoid receptors and therefore, a decreased responsiveness to asthma medication and an increase in asthma symptoms (Grant et al., 2021)

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