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Coronary artery disease occurs when the arteries that supply blood to the heart muscle become narrowed by plaque or blocked by clots

The key difference with smoke-free alternatives is that in general they do not require burning and thus, do not produce smoke

As for heated tobacco products, compared to 2018, smokers who say they have never tried them have decreased by 12 percentage points (from 75% to 62.7%), consequently, Italians who have only tried them are on the rise (from 19% to 22.2%) and, even more, those who have used them (more than doubled compared to 2018) and those who use them regularly (4%), which tripled compared to the previous survey, when they stopped at 1.2%

Cortese and Ling 2011

Mathers, C