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Given that many studies included in this meta-analysis did not report the time elapsed between last cigarette smoked and MRI data collection (Additional file 1: Table S2), this potential confounding factor cannot be ruled out

Two components of counseling are especially effective and clinicians should use these when counseling patients making a quit attempt: Practical counseling (problem-solving/skills training) Social support delivered as part of treatment Dental providers should actively participate in tobacco cessation strategies both at the community level and in private practices

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