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Rolling out expensive medicines is not necessarily needed, he says, as only a small percentage of smokers meet the requirements for this type of treatment
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As of early 2018, the National Academies of Sciences, Engineering, and Medicine (NASEM) concluded that "there is general agreement that the number, size, and quality of studies for judging the effectiveness of e-cigarettes as cessation aids in comparison with cessation aids of proven efficacy are limited, and therefore there is insufficient evidence to permit a definitive conclusion at this time." 199 Further, the long-term health effects associated with use of ENDS are still largely unknown, 200 and FDA has not yet approved any ENDS products as cessation devices
Heavy nicotine use in the form of smoking tobacco has been linked to neuropathy (Brody, 2006), often manifesting as prefrontal gray matter atrophy (Gallinat et al., 2006
