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All of the participants were tested for their levels of the three different enzymes

We extracted 93 observations from 14 prospective cohort studies and 9 casecontrol studies across 14 locations (Supplementary Table 3) 84,87,145,146,147,148,149,150,151,152,153,154,155,156,157,158,159,160,161,162,163,164,165