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14 Patients taking varenicline should be advised to stop treatment and contact a health professional if they notice negative changes in behaviour or thinking, mood swings, anxiety, depression or suicidal ideation

They acknowledge vaping is likely less harmful but emphasize that "less harmful" doesn't mean "harmless," and they warn against using vapes as a gateway product for non-smokers

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Filter microfibres within sediment as a vector for nicotine are therefore anticipated to be less neurologically hazardous than filter toxicants in seawater

The Surgeon General Report in 2006 stated that even separately enclosed, separately exhausted, negative-pressure smoking rooms cannot keep second hand smoke from spilling into adjacent areas