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However, there are a number of risk factors that favour the development of cancer: Smoking (cigarettes or e-cigarettes) Frequent alcohol consumption (especially high-proof alcohol in combination with tobacco consumption) Infection with human papillomavirus (HPV), Eppstein-Barr virus and other viruses Poor oral hygiene Chronic inflammation of the mucous membranes Inflammation at the edge of the tongue due to ill-fitting dentures Unbalanced diet with nitrite-containing foods (e.g